An update on the treatment of mixed bipolar states: what is new in 2013?
Identifieur interne : 000228 ( Main/Exploration ); précédent : 000227; suivant : 000229An update on the treatment of mixed bipolar states: what is new in 2013?
Auteurs : Sami Ouanes [Tunisie] ; Leila Chennoufi [Tunisie] ; Majda Cheour [Tunisie]Source :
- Journal of affective disorders [ 1573-2517 ] ; 2014.
Descripteurs français
- KwdFr :
- Aripiprazole (MeSH), Benzodiazépines (effets indésirables), Benzodiazépines (usage thérapeutique), Calcitonine (effets indésirables), Calcitonine (usage thérapeutique), Composés hétérocycliques avec 4 noyaux ou plus (effets indésirables), Composés hétérocycliques avec 4 noyaux ou plus (usage thérapeutique), Essais contrôlés randomisés comme sujet (MeSH), Humains (MeSH), Neuroleptiques (effets indésirables), Neuroleptiques (usage thérapeutique), Olanzapine (MeSH), Pipérazines (effets indésirables), Pipérazines (usage thérapeutique), Quinolinone (effets indésirables), Quinolinone (usage thérapeutique), Résultat thérapeutique (MeSH), Thiazoles (effets indésirables), Thiazoles (usage thérapeutique), Trouble bipolaire (psychologie), Trouble bipolaire (traitement médicamenteux).
- MESH :
- effets indésirables : Benzodiazépines, Calcitonine, Composés hétérocycliques avec 4 noyaux ou plus, Neuroleptiques, Pipérazines, Quinolinone, Thiazoles.
- psychologie : Trouble bipolaire.
- traitement médicamenteux : Trouble bipolaire.
- usage thérapeutique : Benzodiazépines, Calcitonine, Composés hétérocycliques avec 4 noyaux ou plus, Neuroleptiques, Pipérazines, Quinolinone, Thiazoles.
- Aripiprazole, Essais contrôlés randomisés comme sujet, Humains, Olanzapine, Résultat thérapeutique.
English descriptors
- KwdEn :
- Antipsychotic Agents (adverse effects), Antipsychotic Agents (therapeutic use), Aripiprazole (MeSH), Benzodiazepines (adverse effects), Benzodiazepines (therapeutic use), Bipolar Disorder (drug therapy), Bipolar Disorder (psychology), Calcitonin (adverse effects), Calcitonin (therapeutic use), Heterocyclic Compounds, 4 or More Rings (adverse effects), Heterocyclic Compounds, 4 or More Rings (therapeutic use), Humans (MeSH), Olanzapine (MeSH), Piperazines (adverse effects), Piperazines (therapeutic use), Quinolones (adverse effects), Quinolones (therapeutic use), Randomized Controlled Trials as Topic (MeSH), Thiazoles (adverse effects), Thiazoles (therapeutic use), Treatment Outcome (MeSH).
- MESH :
- chemical , adverse effects : Antipsychotic Agents, Benzodiazepines, Calcitonin, Heterocyclic Compounds, 4 or More Rings, Piperazines, Quinolones, Thiazoles.
- chemical , therapeutic use : Antipsychotic Agents, Benzodiazepines, Calcitonin, Heterocyclic Compounds, 4 or More Rings, Piperazines, Quinolones, Thiazoles.
- chemical : Aripiprazole, Olanzapine.
- drug therapy : Bipolar Disorder.
- psychology : Bipolar Disorder.
- Humans, Randomized Controlled Trials as Topic, Treatment Outcome.
Abstract
UNLABELLED
Although common and severe, mixed states are rarely the subject of proper clinical trials. The aim of this paper is to systematically review data published in 2013 on the pharmacological treatment of mixed states.
METHODS
The Medline database was searched for 2013 publications using the following keywords: 'treatment'; 'mixed'; 'bipolar'.
RESULTS
Medline search returned 118 results. Manual inspection of abstracts allowed selecting six papers for further review. The first meta-analysis of the efficacy of second-generation antipsychotics in mixed episodes, published in 2013, showed the efficacy of these agents. Other papers suggested that asenapine and olanzapine were efficacious for mixed episodes, with olanzapine being equally effective in patients with or without substance abuse. Aripiprazole and ziprasidone were reported to be efficacious and safe in treating manic/mixed episodes in children and adolescents. In another trial, Calcitonin was not found to be superior to placebo in treating manic/mixed episodes.
CONCLUSION
Although data suggest that most agents efficacious for mania may also be efficacious for mixed episodes, further studies are needed to confirm this assumption.
DOI: 10.1016/j.jad.2014.02.001
PubMed: 24655765
Affiliations:
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Le document en format XML
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xml:lang="fr">Tunisie</country><wicri:regionArea>Department of Psychiatry E, Razi Hospital, Manouba</wicri:regionArea><wicri:noRegion>Manouba</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of affective disorders</title><idno type="eISSN">1573-2517</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antipsychotic Agents (adverse effects)</term><term>Antipsychotic Agents (therapeutic use)</term><term>Aripiprazole (MeSH)</term><term>Benzodiazepines (adverse effects)</term><term>Benzodiazepines (therapeutic use)</term><term>Bipolar Disorder (drug therapy)</term><term>Bipolar Disorder (psychology)</term><term>Calcitonin (adverse effects)</term><term>Calcitonin (therapeutic use)</term><term>Heterocyclic Compounds, 4 or More Rings (adverse effects)</term><term>Heterocyclic Compounds, 4 or More Rings (therapeutic use)</term><term>Humans (MeSH)</term><term>Olanzapine (MeSH)</term><term>Piperazines (adverse effects)</term><term>Piperazines (therapeutic use)</term><term>Quinolones (adverse effects)</term><term>Quinolones (therapeutic use)</term><term>Randomized Controlled Trials as Topic (MeSH)</term><term>Thiazoles (adverse effects)</term><term>Thiazoles (therapeutic use)</term><term>Treatment Outcome (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Aripiprazole (MeSH)</term><term>Benzodiazépines (effets indésirables)</term><term>Benzodiazépines (usage thérapeutique)</term><term>Calcitonine (effets indésirables)</term><term>Calcitonine (usage thérapeutique)</term><term>Composés hétérocycliques avec 4 noyaux ou plus (effets indésirables)</term><term>Composés hétérocycliques avec 4 noyaux ou plus (usage thérapeutique)</term><term>Essais contrôlés randomisés comme sujet (MeSH)</term><term>Humains (MeSH)</term><term>Neuroleptiques (effets indésirables)</term><term>Neuroleptiques (usage thérapeutique)</term><term>Olanzapine (MeSH)</term><term>Pipérazines (effets indésirables)</term><term>Pipérazines (usage thérapeutique)</term><term>Quinolinone (effets indésirables)</term><term>Quinolinone (usage thérapeutique)</term><term>Résultat thérapeutique (MeSH)</term><term>Thiazoles (effets indésirables)</term><term>Thiazoles (usage thérapeutique)</term><term>Trouble bipolaire (psychologie)</term><term>Trouble bipolaire (traitement médicamenteux)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antipsychotic Agents</term><term>Benzodiazepines</term><term>Calcitonin</term><term>Heterocyclic Compounds, 4 or More Rings</term><term>Piperazines</term><term>Quinolones</term><term>Thiazoles</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antipsychotic Agents</term><term>Benzodiazepines</term><term>Calcitonin</term><term>Heterocyclic Compounds, 4 or More Rings</term><term>Piperazines</term><term>Quinolones</term><term>Thiazoles</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Aripiprazole</term><term>Olanzapine</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Bipolar Disorder</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Benzodiazépines</term><term>Calcitonine</term><term>Composés hétérocycliques avec 4 noyaux ou plus</term><term>Neuroleptiques</term><term>Pipérazines</term><term>Quinolinone</term><term>Thiazoles</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Trouble bipolaire</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Bipolar Disorder</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Trouble bipolaire</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Benzodiazépines</term><term>Calcitonine</term><term>Composés hétérocycliques avec 4 noyaux ou plus</term><term>Neuroleptiques</term><term>Pipérazines</term><term>Quinolinone</term><term>Thiazoles</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Randomized Controlled Trials as Topic</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Aripiprazole</term><term>Essais contrôlés randomisés comme sujet</term><term>Humains</term><term>Olanzapine</term><term>Résultat thérapeutique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>UNLABELLED</b></p><p>Although common and severe, mixed states are rarely the subject of proper clinical trials. The aim of this paper is to systematically review data published in 2013 on the pharmacological treatment of mixed states.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>The Medline database was searched for 2013 publications using the following keywords: 'treatment'; 'mixed'; 'bipolar'.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Medline search returned 118 results. Manual inspection of abstracts allowed selecting six papers for further review. The first meta-analysis of the efficacy of second-generation antipsychotics in mixed episodes, published in 2013, showed the efficacy of these agents. Other papers suggested that asenapine and olanzapine were efficacious for mixed episodes, with olanzapine being equally effective in patients with or without substance abuse. Aripiprazole and ziprasidone were reported to be efficacious and safe in treating manic/mixed episodes in children and adolescents. In another trial, Calcitonin was not found to be superior to placebo in treating manic/mixed episodes.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Although data suggest that most agents efficacious for mania may also be efficacious for mixed episodes, further studies are needed to confirm this assumption.</p></div></front></TEI><affiliations><list><country><li>Tunisie</li></country></list><tree><country name="Tunisie"><noRegion><name sortKey="Ouanes, Sami" sort="Ouanes, Sami" uniqKey="Ouanes S" first="Sami" last="Ouanes">Sami Ouanes</name></noRegion><name sortKey="Chennoufi, Leila" sort="Chennoufi, Leila" uniqKey="Chennoufi L" first="Leila" last="Chennoufi">Leila Chennoufi</name><name sortKey="Cheour, Majda" sort="Cheour, Majda" uniqKey="Cheour M" first="Majda" last="Cheour">Majda Cheour</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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